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Nacubactam (b)
CAS No. 2007923-17-1
Nacubactam (b)( OP 0595 | RG 6080 | RO 7079901 )
Catalog No. M13133 CAS No. 2007923-17-1
Nacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 963 | In Stock |
|
| 50MG | 1962 | In Stock |
|
| 100MG | 2520 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNacubactam (b)
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NoteResearch use only, not for human use.
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Brief DescriptionNacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM.
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DescriptionNacubactam (OP 0595, RG 6080, RO 7079901) is a diazabicyclooctane that inhibits class A and C β-lactamases with IC50 of <1 uM, also acts as a PBP2-active antibacterial; exhibits MICs of 0.5 to 4 μg/ml for most members of the family Enterobacteriaceae, owing to inhibition of PBP2; has MICs of 1-4 mg/ml for Escherichia coli, Enterobacter, Citrobacter and Klebsiella spp; increases the antibacterial activity of cefepime in both in vitro and in vivo.Bacterial Infection Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsOP 0595 | RG 6080 | RO 7079901
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaInfection
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IndicationBacterial Infection
Chemical Information
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CAS Number2007923-17-1
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Formula Weight342.323
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Molecular FormulaC9H18N4O8S
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Purity>98% (HPLC)
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Solubility——
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SMILESC1CC(N2CC1N(C2=O)OS(=O)(=O)O)C(=O)NOCCN.O
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Chemical Name(2S, 5R)-N-(2-Aminoethoxy)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide, monohydrate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Morinaka A, et al. J Antimicrob Chemother. 2015 Oct;70(10):2779-86.
2. Livermore DM, et al. J Antimicrob Chemother. 2015 Nov;70(11):3032-41.
3. Livermore DM, et al. Antimicrob Agents Chemother. 2015 Nov 9;60(1):554-60.
4. Morinaka A, et al. J Antibiot (Tokyo). 2017 Mar;70(3):246-250.
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